Peripheral elimination of the sympathetic nervous system stimulates immunocyte retention in lymph nodes and ameliorates collagen type II arthritis
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- 作者：Susanne Klatt ; Hubert Stangl ; Julia Kunath ; Torsten Lowin ; Georg Pongratz ; Rainer H. Straub ; rainer.straub@ukr.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sympathetic nervous system ; Leukocyte egress ; Leukocyte entry ; Secondary lymphoid organ ; Arthritis
- 刊名：Brain, Behavior, and Immunity
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：54
- 期：Complete
- 页码：201-210
- 全文大小：2465 K
文摘
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Collagen-induced arthritis increased energy consumption in lymph nodes and spleen.
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Sympathectomy increased energy consumption in lymph nodes and spleen.
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Sympathectomy reduced arthritis severity but increased number of lymph node cells.
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Sympathectomy increased lymph node cell entry and decreased cell egress signals.
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Sympathectomy-retained leukocytes of lymph nodes markedly aggravated arthritis.