Analysis of ANKKI (rs1800497) and DRD2 (rs1079597, rs1800498) variants in five ethnic groups from Punjab, North-West India
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- 作者：Gagandeep Singha ; b ; Indu Talwara ; Rubina Sharmab ; Harkirat Singh Sandhub ; Kawaljit Matharoob ; matharookawal@gmail.com" class="auth_mail" title="E-mail the corresponding author ; A.J.S. Bhanwerb ; ajsbhanwer@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AMOVA ; analysis of molecular variance ; ANKKI ; ankyrin repeat and kinase domain containing 1 ; DRD2 ; Dopamine D2 receptor ; FST ; inter- population diversity ; HS ; Intra-population diversity ; HT ; total genomic diversity ; LD ; linkage disequilibrium ; POPGENE ; population genetic analysis program ; PCR-RFLP ; polymerase chain reaction-restriction fragment length polymorphism ; SNP ; single nucleotide polymorphism ; MDS ; multidimensional scaling
- 刊名：Gene
- 出版年：2016
- 出版时间：10 June 2016
- 年：2016
- 卷：584
- 期：1
- 页码：69-74
- 全文大小：681 K
文摘
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We examined genetic structure and affinity among five ethnic groups of Punjab.
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Three SNPs of ANKKI and DRD2 gene were analyzed.
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High heterozygosity was observed at three studied loci.
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These ethnic groups share closeness with each other and represent genomic uniformity.