The effect of long-term hindlimb unloading on the expression of risk neurogenes encoding elements of serotonin-, dopaminergic systems and apoptosis; comparison with the effect of actual spaceflight on mouse brain
Hindlimb unloading increased the expression of dopanimergic genes in striatum. Hippocampus Bcl-xl expression was similar for hindlimb unloading and spaceflight. Hindlimb unloading did not alter the expression of MAOA and 5-HT2A receptor genes.