The association between insulin resistance and depression in the Korean general population

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• 作者：Jae-Hon Lee^a ; ^b ; ^c ; ¹ ; Sung Keun Park^d ; ¹ ; Jae-Hong Ryoo^e ; Chang-Mo Oh^f ; Rodrigo B. Mansur^a ; ^b ; ^g ; Jeffrey E. Alfonsi^h ; Danielle S. Cha^a ; Yena Lee^a ; ⁱ ; Roger S. McIntyre^a ; ^b ; ⁱ ; ^j ; ^{Roger.McIntyre@uhn.ca} ; Ju Young Jung^d ; ^e ; ^{jjy0501@naver.com}
• 关键词：Depression ; Insulin resistance ; Cross-sectional study ; General population
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：208
• 期：Complete
• 页码：553-559
• 全文大小：229 K
• 卷排序：208

文摘

Increased insulin resistance was associated with depressive symptoms in the Korean general population (N=165,443). The subgroup analysis revealed the association was statistically significant in female, non-diabetic and young groups. Increased insulin resistance in non-diabetic participants was more strongly associated with depressive symptoms. These findings suggest that early management of insulin resistance may prevent progression toward depressive symptoms.