Coupled experimental-modeling analyses of heat transfer in ex-vivo VS55-perfused porcine hepatic tissue being plunged in liquid nitrogen for vitreous cryopreservation
刊名:International Journal of Heat and Mass Transfer
出版年:2017
出版时间:March 2017
年:2017
卷:106
期:Complete
页码:970-979
全文大小:2925 K
卷排序:106
文摘
A coupled experimental-modeling analyses of heat transfer in large scale biomaterials during vitrification cryopreservation was successfully developed. Thermal conductivities of VS55 and the VS55-perfused porcine hepatic tissue at −196 to 37 °C were measured. The convective heat transfer coefficients on the outer surface of a cryovial plunged into liquid nitrogen were determined with an inverse problem method. The heat transfer in ex-vivo VS55-perfused porcine hepatic tissue being plunged in LN2 for vitreous cryopreservation was precisely modelled.