Porcine parvovirus capsid protein expressed in Escherichia coli self-assembles into virus-like particles with high immunogenicity in mice and guinea pigs
Porcine parvovirus VP2 protein expressed in E.coli cells self-assembled into VLPs. PPV VLPs showed hemagglutination activity with high titer. Vaccination with PPV VLPs could protect guinea pigs from virus challenge.