We studied interactions among Toxoplasma gondii seropositivity, plasma kynurenine, history of suicide attempts, and schizophrenia.
Elevated kynurenine was associated with history of NF-SSDV only in schizophrenia patients seropositive for T. gondii.
T. gondii and KYN may have a nonlinear cumulative effect on the risk of NF-SSDV in patients with schizophrenia.