Combined Toxoplasma gondii seropositivity and high blood kynurenine - Linked with nonfatal suicidal self-directed violence in patients with schizophrenia
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- 作者：Olaoluwa Okusagaa ; b ; Erica Duncanc ; Patricia Langenbergd ; Lena Brundine ; Dietmar Fuchsf ; Maureen W. Groerg ; Ina Gieglingh ; Kelly A. Stearns-Yoderi ; j ; Annette M. Hartmannh ; Bettina Konteh ; Marion Friedlh ; Lisa A. Brenneri ; j ; k ; l ; m ; Christopher A. Lowryj ; n ; Dan Rujescuh ; 1 ; Teodor T. Postolachea ; i ; j ; o ; 1 ; tpostolache@psych.umaryland.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Toxoplasma gondii ; Kynurenine ; Schizophrenia ; Non-fatal suicidal self-directed violence
- 刊名：Journal of Psychiatric Research
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：72
- 期：Complete
- 页码：74-81
- 全文大小：322 K
文摘
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We studied interactions among Toxoplasma gondii seropositivity, plasma kynurenine, history of suicide attempts, and schizophrenia.
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Elevated kynurenine was associated with history of NF-SSDV only in schizophrenia patients seropositive for T. gondii.
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T. gondii and KYN may have a nonlinear cumulative effect on the risk of NF-SSDV in patients with schizophrenia.