Developmental expression of Kv1 voltage-gated potassium channels in the avian hypothalamus
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- 作者：Megan A. Doczia ; mdoczi@norwich.edu" class="auth_mail" title="E-mail the corresponding author ; Carl M. Vitzthuma ; Cynthia J. Forehandb
- 关键词：Kv1 ; Shaker family voltage-gated potassium channel ; E8 ; embryonic day 8 ; E12 ; embryonic day 12 ; aCSF ; artificial cerebrospinal fluid ; Opt ; optic tract ; 3v ; third ventricle ; ARC ; arcuate nucleus ; VMH ; ventromedial hypothalamus ; ME ; median eminence ; Elec ; electrode
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：11 March 2016
- 年：2016
- 卷：616
- 期：Complete
- 页码：182-188
- 全文大小：1314 K
文摘
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Avian hypothalamic neurons demonstrate a developmental increase in outward current.
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E12 hypothalamic neurons exhibit robust phasic action potentials compared to E8.
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Kv1.2, Kv1.3, and Kv1.5 mRNA is present in embryonic avian hypothalamic neurons.
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Increase in Kv1.2 and Kv1.5 likely contributes to electrophysiological changes.