Rabbit CD200R binds host CD200 but not CD200-like proteins from poxviruses
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- 作者：Munir Akkaya ; 1 ; munir.akkaya@nih.gov" class="auth_mail" title="E-mail the corresponding author ; Lai-Shan Kwong ; Erdem Akkaya2 ; Deborah Hatherley ; A. Neil Barclay
- 关键词：CD200 ; CD200R ; Myxoma virus ; M141 ; Poxviruses
- 刊名：Virology
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：488
- 期：Complete
- 页码：1-8
- 全文大小：3133 K
文摘
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The coding sequences of rabbit CD200 and rabbit CD200R have been identified.
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Rabbit CD200-CD200R binding resembles CD200-CD200R interactions in other species.
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Poxvirus CD200-like molecules (M141, SFV 141) do not interact with rabbit CD200R.
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M141 can downregulate immune response without utilizing host CD200R.