Temporo-mesial extraventricular neurocytoma and cortical dysplasia in focal temporal lobe epilepsy
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- 作者：Marco Giulioni ; Matteo Martinoni ; Guido Rubboli ; Gianluca Marucci ; Anna Federica Marliani ; Stella Battaglia ; Filippo Badaloni ; Eugenio Pozzati ; Fabio Calbucci
- 关键词：Cortical dysplasias ; Epilepsy surgery ; Extraventricular neurocytoma ; Glioneuronal tumors ; Pharmacoresistant epilepsy
- 刊名：Journal of Clinical Neuroscience
- 出版年：2011
- 出版时间：January 2011
- 年：2011
- 卷：18
- 期：1
- 页码：147-148
- 全文大小：267 K
文摘
We describe a 17-year-old boy with a left extraventricular temporo-mesial neurocytoma associated with cortical dysplasia causing focal pharmacoresistant temporal lobe epilepsy. He presented with a long history of medically refractory, temporal complex partial seizures. MRI showed a left temporo-mesial lesion suspect to be a low-grade tumor. Based on the pre-operative non-invasive neurophysiological studies, the patient underwent a left tailored temporal antero-mesial resection. Histopathological examination showed an extraventricular neurocytoma associated with architectural dysplasia (Type 1a) of the temporal pole. The patient was seizure-free at 2 years follow-up. Extraventricular neurocytomas must be considered in the differential diagnosis of the plethora of low-grade tumors associated with focal epilepsy that typically involve the temporal lobe, and are frequently associated with focal cortical dysplasia.