The Taming of the NF-¦ÊB: PP4R1 Navigates while PP4c Dephosphorylates

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• 作者：Anastasia Tikhonova ; Iannis Aifantis
• 刊名：Immunity
• 出版年：2012
• 出版时间：19 October, 2012
• 年：2012
• 卷：37
• 期：4
• 页码：594-596
• 全文大小：267 K

文摘

The NF-¦ÊB signaling pathway is important in the regulation of physiological and malignant hematopoiesis. In this issue of Immunity, identify a phosphatase, PP4R1, that inhibits NF-¦ÊB activation in T?cells and T?cell lymphoma.