Bone morphogenetic protein 15 may promote follicle selection in the hen
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- 作者：C.S. Stephens ces277@cornell.edu" class="auth_mail" title="E-mail the corresponding author ; P.A. Johnson ; paj1@cornell.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：BMP15 ; Hen ; Ovary ; AMH ; Ovarian follicle
- 刊名：General and Comparative Endocrinology
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：235
- 期：Complete
- 页码：170-176
- 全文大小：658 K
文摘
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BMP15 expression, regulation and function were examined in the hen ovary.
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BMP15 is in the oocyte and expression is increased at around follicle selection.
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Estradiol increases BMP15 mRNA expression in vitro.
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BMP15 increases FSHR mRNA and decreases AMH mRNA and OCLN mRNA and protein.
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Results provide evidence that the oocyte promotes follicle selection in the hen.