Unprecedented ‘ring transformation-rearrangement’ of pyran-2-ones into 5,6-dihydropyran-2-ones through insertion of acetol
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- 作者：Amit Kumar ; Salil P. Singh ; Deepti Verma ; Ruchir Kant ; Prakas R. Maulik ; Atul Goel
- 关键词：5 ; 6-Dihydropyran-2-ones ; Pyran-2-ones ; Acetol ; Ring transformation-rearrangement reaction
- 刊名：Tetrahedron Letters
- 出版年：2010
- 出版时间：10 February 2010
- 年：2010
- 卷：51
- 期：6
- 页码：961-965
- 全文大小：466 K
文摘
One-pot efficient synthesis of functionalized 5,6-dihydropyran-2-ones has been delineated by reacting 2H-pyran-2-ones and acetol in the presence of a base at room temperature. The formation of 5,6-dihydropyran-2-ones revealed that the reaction proceeded in a unique ‘ring transformation-rearrangement’ sequence.