Immunological evidence of Zika virus transmission in Thailand

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• 作者：Nitwara Wikan¹ ; Yupin Suputtamongkol² ; Sutee Yoksan¹ ; Duncan R. Smith¹ ; ^{duncan_r_smith@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Prasert Auewarakul²
• 关键词：Emerging infectious diseases ; Serosurvey ; Thailand ; Zika virus
• 刊名：Asian Pacific Journal of Tropical Medicine
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：9
• 期：2
• 页码：141-144
• 全文大小：442 K

文摘

To identify immunological evidence of Zika virus transmission in Thailand.

Methods

To undertake a preliminary serosurvey of possible exposure to Zika virus, 21 serum samples from cohort of acute undifferentiated fever patients were examined for immunoreactivity to Zika, Dengue, Japanese encephalitis and Chikungunya envelope antigens by Western blot analysis.

Results

Twenty of the 21 serum samples showed immunoreactivity to at least one of the antigens, with seven samples showing immunoreactivity to all antigens. Of particular note, two serum samples showed immunoreactivity only to Zika envelope antigen, with no immunoreactivity to other envelope antigens.

Conclusions

This study presents the first evidence of Zika virus transmission in Thailand, although as yet the relationship between transmission and possible cases of Zika fever in Thailand requires further investigation.