Synthesis of phenanthridinones using Cu- or Pd-mediated CN bond formation

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• 作者：Prattya Nealmongkol^a ; Jordan Calmes^b ; Somsak Ruchirawat^a ; ^b ; ^c ; Nopporn Thasana^a ; ^b ; ^c ; ^{nopporn@cri.or.th}
• 关键词：Copper ; Palladium ; CN bond formation ; Phenanthridinone ; Lactam
• 刊名：Tetrahedron
• 出版年：2017
• 出版时间：9 February 2017
• 年：2017
• 卷：73
• 期：6
• 页码：735-741
• 全文大小：1102 K
• 卷排序：73

文摘

The chemoselective synthesis of phenanthridinones was studied using copper(I)- and palladium(II)-catalyzed CN bond formation with various bases, ligands, and solvents. Phenanthridinones were obtained from 2-halobiarylcarboxylates and amines in a one-pot reaction. The phenanthridinones and heterocyclic-fused lactam derivatives were accomplished using developed methods.