Interaction of different statins with model membranes by NMR data

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• 作者：L.F. Galiullina ; ^{lgaliull@kpfu.ru} ; O.V. Aganova ; I.A. Latfullin ; G.S. Musabirova ; A.V. Aganov ; V.V. Klochkov
• 关键词：NMR ; Molecular complex ; Dodecylphosphocholine ; Micelles ; Statins
• 刊名：Biochimica et Biophysica Acta (BBA) - Biomembranes
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：1859
• 期：3
• 页码：295-300
• 全文大小：1385 K
• 卷排序：1859

文摘

NMR study showed that statins form molecular complexes with model membranes. Pravastatin, simvastatin, fluvastatin, cerivastatin have different locations in DPC micelles. Location of statins in model membranes can explain their pharmacological differences.