Potential and specific use of MWCNT-MnO2/PPy nano-composite as anode in MFC. Modification of CC with MWCNT-MnO2/PPy improved biocompatibility of anode. MWCNT-MnO2/PPy on CC has the increased surface area and the reduced resistance. The maximum power density of 1125.4 mW m−2, 368.92% higher than control.