Enantioselective benzoin condensation catalyzed by spirocyclic terpene-based N-heterocyclic carbenes

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• 作者：Zbigniew Rafiński ^{payudo@chem.umk.pl" class="auth_mail" title="E-mail the corresponding author}
• 关键词：N-Heterocyclic carbenes ; Benzoin condensation ; Asymmetric synthesis ; Acyloins ; Terpenoids
• 刊名：Tetrahedron
• 出版年：2016
• 出版时间：14 April 2016
• 年：2016
• 卷：72
• 期：15
• 页码：1860-1867
• 全文大小：697 K

文摘

The synthesis of new chiral spirocyclic triazolium salts, derived from (1S)-fenchone and (1R)-camphorquinone, are described. These salts, which are N-heterocyclic carbene precatalysts, were successfully employed in the catalytic asymmetric benzoin condensation affording acyloins with good yields and moderate enantioselectivities.