Using a serial dilution of human blood (1:10–1:10000), extraction utilizing BTA showed higher DNA yields compared to the extraction with Chelex/iPrep™. There was no DNA detected for dilutions 1:5000 and 1:10000 with Chelex/iPrep™, whereas BTA-extraction obtained enough DNA for full NGM SElect™ profiles. For mock samples of touch DNA on cotton fabric, higher DNA yields were gained with PrepFiler® Express BTA extraction. Better profiling results were also gained with BTA extraction for the blood dilution series as well as the touch DNA mock traces. Although lysis with BTA is still challenging since the BTA with a maximum of 230 μl lysis buffer does not cover an intact tape (experiments were consequently carried out with halves of minitapes), this study reveals that BTA has a higher extraction efficiency for Scenesafe FAST™ minitapes than Chelex/iPrep™.