Decreased vaccine antibody titers following exposure to multiple metals and metalloids in e-waste-exposed preschool children

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• 作者：Xinjiang Lin^a ; ¹ ; Xijin Xu^a ; ^b ; ¹ ; Xiang Zeng^a ; ^c ; Long Xu^a ; Zhijun Zeng^a ; ^c ; Xia Huo^d ; ^{xhuo@jnu.edu.cn}
• 关键词：Metals ; Metalloids ; Electronic waste ; Vaccine antibodies ; Preschool children
• 刊名：Environmental Pollution
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：220
• 期：part_PA
• 页码：354-363
• 全文大小：1092 K
• 卷排序：220

文摘

We examined the associations of multiple heavy metals and metalloids with seven vaccine antibodies. Higher levels of blood Pb, Mn, Cu, Zn and Cr were found in children from the e-waste- polluted area. All vaccine antibodies Levels except hepatitis B were significantly reduced in the exposed area. High blood Pb, Cu and Zn were observed to be inversely associated with seven antibody titers. Multiple heavy metal and metalloid exposure may inhibit child antibody levels against vaccines.