Hemipelvectomy for the treatment of high-grade sarcomas: Pronostic of chondrosarcomas compared to other histological types

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• 作者：J. Arnal-Burró ; ^a ; ^b ; ^{Juanarnal@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; J.A. Calvo-Haro^a ; ^b ; ^c ; C. Igualada-Blazquez^a ; ^b ; P. Gil-Martí ; nez^a ; ^b ; M. Cuervo-Dehesa^a ; ^b ; J. Vaquero-Martí ; n^a ; ^b ; ^c
• 关键词：Hemipelvectomy ; High grade sarcomas ; Pelvic sarcoma ; Pelvic chondrosarcoma ; Survival
• 刊名：Revista Española de Cirugía Ortopédica y Traumatología
• 出版年：2016
• 出版时间：January-February 2016
• 年：2016
• 卷：60
• 期：1
• 页码：67-74
• 全文大小：1963 K

文摘

The low incidence and histological heterogeneity of primary sarcomas located in the pelvis make it difficult to find homogeneous cohorts.

Objective

To describe the life and functional prognosis depending on the histological type of sarcoma in a series of locally advanced high-grade pelvis located sarcomas treated by hemipelvectomy.

Methods

A descriptive epidemiological and functional study was conducted on 15 cases treated between 2006 and 2012. Survival analysis, functional assessment, and a comparative study by histological type were performed, comparing chondrosarcomas to other histological diagnoses.

Results

The most frequent histological type was chondrosarcoma (46%), and the most frequent location was P2 (periacetabular) (73%). An internal hemipelvectomy was performed in 66% of cases, with a higher incidence (83%) in chondrosarcomas. Overall two-year survival was 54%, with higher survival in the chondrosarcoma group (67%) than in the other sarcomas (43%). Functional status depended on the type of intervention, with no differences in histological type or the performance of the reconstruction.

Discussion and conclusions

Hemipelvectomy is a surgical procedure that is indicated for the treatment of locally advanced high grade pelvis located sarcomas, regardless of histological type. The incidence of limb preservation and overall survival is higher in chondrosarcomas compared to other sarcomas.