Therapy and Prevention of Postoperative Urosepsis of Ureter Endoscopic Lithotripsy for “Non-infection‿

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• 作者：Jun Shen^a ; ^b ; Fa Sun^b ; Fang-min Chen^b ; Zhi-ping Wu^b ; Sheng-wen Li^a ; ^c ; ^{swli@tsinghua.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：lithotripsy ; non-infection ; ureter ; urosepsis
• 刊名：Chinese Medical Sciences Journal
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：31
• 期：1
• 页码：49-53

文摘

To analyze the risk factors causing postoperative urosepsis in ureter endoscopic lithotripsy without infection preoperatively, in order to make a more effective and safer preventive and therapeutic strategy.

Methods

From January 2010 to January 2015, 5 ureteral calculus patients undergoing ureter endoscopic lithotripsy with holmium laser were retrospectively enrolled in this clinical study. These patients suffered urosepsis postoperatively confirmed by the clinical presentations and laboratory results, while they had no infection in their blood and urine preoperatively. Without delay, 5 patients were treated by anti-inflammation and anti-shock.

Results

The vasopressor drug was stopped gradually after 12-36 hours. The body temperature was recovered to normal in 2 or 3 days, and the blood and urine test results were not abnormal in 7 days. At last, 5 patients were all cured.

Conclusions

Stone and operation themselves are potential factors to cause urosepsis after ureter endoscopic lithotripsy. Especially for patients who had not presented infection preoperatively, careful preparation preoperatively, corrective manipulation, low pressure irrigation, drainage and controlling time during operation, and early diagnosis, appropriate treatment postoperatively are the key to cure and prevent urosepsis.