New p-terphenyls from the endophytic fungus Aspergillus sp. YXf3

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• 作者：Wei Yan^a ; ¹ ; Wuringege^b ; ¹ ; Sui-Jun Li^c ; Zhi-Kai Guo^d ; Wen-Jing Zhang^c ; Wei Wei^c ; Ren-Xiang Tan^c ; Rui-Hua Jiao^c ; ^{rhjiao@nju.edu.cn}
• 关键词：p-Terphenyls ; Aspergillus sp. ; Anti-phytopathogenic activity
• 刊名：Bioorganic & Medicinal Chemistry Letters
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：27
• 期：1
• 页码：51-54
• 全文大小：468 K
• 卷排序：27

文摘

Five new p-terphenyls named prenylterphenyllin D (1), prenylterphenyllin E (2), 2′-O-methylprenylterphenyllin (3), 4-O-methylprenylterphenyllin (4) and 3′-O-methylterphenyllin (5) together with seven known compounds (6–12), were isolated from cultures of Aspergillus sp. YXf3. The structures of the new compounds were elucidated by extensive MS and NMR analyses. The NMR and MS data of 5 is reported for the first time, as its structure was listed in SciFinder Scholar with no associated reference. Compounds 6 and 7 were distinguished from each other on the basis of 2D NMR experiments. Compounds 1, 2, 3 and 8 showed antibacterial activities against X. oryzae pv. oryzicola Swings and E. amylovora with the same MIC values of 20 μg/mL while 10 exhibited activities against E. amylovora with an MIC value of 10 μg/mL.