cAMP regulates the functional activity, coupling efficiency and structural organization of mammalian FOF1 ATP synthase
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- 作者：Domenico De Rasmoa ; d.derasmo@ibbe.cnr.it" class="auth_mail" title="E-mail the corresponding author ; Loris Micellib ; Arcangela Santeramob ; Anna Signorileb ; Paolo Lattanzioa ; Sergio Papaa ; b
- 关键词：8-Br-cAMP ; 8-Bromoadenosine 3&prime ; 5&prime ; -cyclic monophosphate ; KH7 ; (E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N&prime ; -(5-bromo-2-hydroxybenzylidene)propanehydrazide ; CAI ; carbonic anhydrase inhibitor ; PKA ; cAMP dependent protein kinase ; PKI ; protein kinase inhibitor ; mPTP ; mitochondrial permeability transition pore ; RLM ; rat liver mitochondria ; sAC ; soluble adenylyl cyclase ; tmAC ; transmembrane adenylyl cyclase
- 刊名：Biochimica et Biophysica Acta (BBA) - Bioenergetics
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：1857
- 期：4
- 页码：350-358
- 全文大小：1303 K
文摘
- 5">
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5">cAMP promotes activity and coupling in mitochondrial FOF1 ATP synthase complex.
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Preserves stability of stalk subunits and oligomerization of the complex
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5">Prevents leak conductance in the complex