Powder-based 3D printing for bone tissue engineering

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• 作者：G. Brunello^a ; ^{giulia-bru@libero.it" class="auth_mail" title="E-mail the corresponding author} ; S. Sivolella^a ; ^{stefano.sivolella@libero.it" class="auth_mail" title="E-mail the corresponding author} ; R. Meneghello^b ; ^{roberto.meneghello@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; L. Ferroni^c ; ^{letizia.ferroni@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; C. Gardin^c ; ^{chiara.gardin@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; A. Piattelli^d ; ^{apiattelli@unich.it" class="auth_mail" title="E-mail the corresponding author} ; B. Zavan^c ; ^{barbara.zavan@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; E. Bressan^a ; ^{eriberto.bressan@unipd.it" class="auth_mail" title="E-mail the corresponding author}
• 关键词：3D printing ; Bone ; Scaffold ; Additive manufacturing technologies ; Powder ; Binder ; Depowdering ; Sintering
• 刊名：Biotechnology Advances
• 出版年：2016
• 出版时间：September-October 2016
• 年：2016
• 卷：34
• 期：5
• 页码：740-753
• 全文大小：1175 K

文摘

Bone tissue engineered 3-D constructs customized to patient-specific needs are emerging as attractive biomimetic scaffolds to enhance bone cell and tissue growth and differentiation.

The article outlines the features of the most common additive manufacturing technologies (3D printing, stereolithography, fused deposition modeling, and selective laser sintering) used to fabricate bone tissue engineering scaffolds. It concentrates, in particular, on the current state of knowledge concerning powder-based 3D printing, including a description of the properties of powders and binder solutions, the critical phases of scaffold manufacturing, and its applications in bone tissue engineering. Clinical aspects and future applications are also discussed.