Altered relation of the renin-aldosterone system and vasoactive peptides in type 2 diabetes: The KORA F4 study
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- 作者：Cornelia Thena ; b ; cornelia.then@med.uni-muenchen.de" class="auth_mail" title="E-mail the corresponding author ; Marietta Rottenkolbera ; Andreas Lechnera ; b ; Christa Meisingerc ; Margit Heierc ; Wolfgang Koenigd ; e ; f ; Annette Petersc ; g ; Wolfgang Rathmannh ; Martin Bidlingmaiera ; Martin Reinckea ; Jochen Seisslera ; b
- 关键词：Diabetes ; Renin ; Aldosterone ; Adrenomedullin ; ANP ; MR-proANP ; MR-proADM
- 刊名：Atherosclerosis
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：252
- 期：Complete
- 页码：88-96
- 全文大小：296 K
文摘
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Renin and aldosterone are inversely associated with midregional-pro atrial natriuretic peptide (MR-proANP).
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Renin and aldosterone are directly associated with midregional-pro adrenomedullin (MR-proADM).
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These associations are diminished or abolished in diabetic subjects.
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Renin and aldosterone are not directly associated with intima media thickness (IMT) in the general community.
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Aldosterone is directly associated with IMT in diabetic subjects.