Proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves regulate lipid metabolism and glucose consumption by activating AMPK pathway in HepG2 cells

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• 作者：Yu Zhang ; Shiguo Chen ; Chaoyang Wei ; Jianchu Chen ; Xingqian Ye ; ^{psu@zju.edu.cn}
• 关键词：Proanthocyanidins ; Chinese bayberry leaves ; Lipid metabolism ; Glucose metabolism ; AMPK
• 刊名：Journal of Functional Foods
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：29
• 期：Complete
• 页码：217-225
• 全文大小：2459 K
• 卷排序：29

文摘

BLPs reduced the activity of pancreatic lipase. SPBLPs and UDBLPs significantly activated AMPK in dose dependent manner. SPBLPs and UDBLPs reduced triglycerides synthesis by phosphorylating ACC. SPBLPs and UDBLPs reduced sterols biosynthesis by mainly inhibiting SREBP-1. SPBLPs promoted glucose consumption in HepG2 cells.