Role of epistasis on the fixation probability of a non-mutator in an adapted asexual population
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- 作者：Ananthu James ananthujms@jncasr.ac.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：Epistasis ; Fixation probability ; Mutators ; Branching process
- 刊名：Journal of Theoretical Biology
- 出版年：2016
- 出版时间：21 October 2016
- 年：2016
- 卷：407
- 期：Complete
- 页码：225-237
- 全文大小：1321 K
文摘
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Fixation probability of a single nonmutator is studied.
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Nonmutator has an indirect selective advantage.
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A multitype branching process is used in the model.
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Antagonistic epistasis lowers the fixation probability of nonmutator.
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Synergistic epistasis enhances the chances of mutation rate reduction.