Growth factors and beta-tricalcium phosphate in the treatment of periodontal intraosseous defects: A systematic review and meta-analysis of randomised controlled trials
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- 作者：Claudiu Cã ; lin ; claudiu_m_calin@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Ion Pã ; traşcu
- 关键词：rhPDGF-BB ; recombinant human platelet-derived growth factor-BB ; rhGDF-5 ; recombinant human growth/differentiation factor-5 ; β-TCP ; beta-tricalcium phosphate ; RCT(s) ; randomised controlled trial(s) ; GF(s) ; growth factor(s) ; PPD ; probing pocket depth ; CAL ; clinical attachment level gain ; GR ; gingival recession ; LBG ; linear bone growth ; %BF ; per cent bone fill
- 刊名：Archives of Oral Biology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：66
- 期：Complete
- 页码：44-54
- 全文大小：599 K
文摘
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5 randomised controlled trials (RCTs) were included in the review.
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RCTs were analysed using the CONSORT guidelines and the Cochrane risk of bias tool.
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Growth factors combined with beta-tricalcium phosphate (β-TCP) improved all outcomes.
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β-TCP alone resulted in less improved clinical and radiographic outcomes.
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Only a difference in gingival recession was observed between different growth factors.