Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer
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- 作者：Carlota Claussena ; 1 ; Alma-Verena Rauschb ; 1 ; Susanne Leziusc ; Ali Amirkhosravid ; Monica Davilad ; John L. Francisd ; Yohei M. Hisadae ; Nigel Mackmane ; Carsten Bokemeyera ; Barbara Schmalfeldtb ; Sven Mahnerf ; Florian Langera ; langer@uke.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tissue factor ; Ovarian cancer ; Microvesicles ; D-dimer ; Venous thromboembolism
- 刊名：Thrombosis Research
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：141
- 期：Complete
- 页码：39-48
- 全文大小：1016 K
文摘
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Preoperative levels of MV TF PCA are increased in patients with ovarian cancer.
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MV TF PCA is not correlated with the tumor stage.
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Addition of MV TF PCA confers diagnostic benefit to D-dimer and CA-125.
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Assessment of MV TF PCA cannot be replaced by quantification of plasma TF antigen.