EP400 Deposits H3.3 into Promoters and Enhancers during Gene Activation
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- 作者：Suman K. Pradhan1 ; Trent Su1 ; Linda Yen2 ; Karine Jacquet3 ; Chengyang Huang1 ; Jacques Cô ; té ; 3 ; Siavash K. Kurdistani1 ; 2 ; Michael F. Carey1 ; 2 ; mcarey@mednet.ucla.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：EP400 ; H3.3 ; H2AZ ; RNA polymerase II ; pre-initiation complex (PIC) ; histone exchange
- 刊名：Molecular Cell
- 出版年：2016
- 出版时间：7 January 2016
- 年：2016
- 卷：61
- 期：1
- 页码：27-38
- 全文大小：3093 K
文摘
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Double-variant H2AZ-H3.3-containing chromatin stimulates transcription in vitro
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EP400 contributes to gene activation in vivo and in vitro
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EP400 is necessary for H2AZ and H3.3 deposition into enhancers and promoters in vivo
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Purified EP400 exchanges both H2AZ and H3.3 into canonical chromatin in vitro