Antimicrobial growth promoter use in livestock: a requirement to understand their modes of action to develop effective alternatives

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• 作者：Kirsty Brown^a ; Richard R.E. Uwiera^b ; Martin L. Kalmokoff^c ; Steve P.J. Brooks^d ; G. Douglas Inglis^a ; ^{douglas.inglis@agr.gc.ca}
• 关键词：Antimicrobial agent ; Antimicrobial growth promoter ; Gastrointestinal health ; Livestock agriculture ; Mechanisms of action ; Alternatives
• 刊名：International Journal of Antimicrobial Agents
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：49
• 期：1
• 页码：12-24
• 全文大小：2232 K
• 卷排序：49

文摘

Antimicrobial growth promoters (AGPs) enhance animal health and improve agricultural productivity. Mechanisms of AGP action are poorly understood; research has diverged into host- and bacteria-centric hypotheses. Due to risks of antimicrobial resistance, AGPs are being phased out of livestock production. Understanding the mechanisms of AGP action is critical in developing effective non-antibiotic alternatives.