刊名:Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
出版年:2017
出版时间:February 2017
年:2017
卷:1860
期:2
页码:196-204
全文大小:1445 K
卷排序:1860
文摘
Human PRE-PIK3C2B interacts with activating as well as repressive complexes. hPRE-PIK3C2B as a transgene has a similar regulatory role in D. melanogaster. The binding of trithorax and PRC2 complex is inversely related to each other. hPRE-PIK3C2B in transgenic flies interacts with both Pc and Trx proteins. The localization of the repressive complex at hPRE-PIK3C2B is the default state.