One facile magnetic SSB-linked aptamer colorimetric assay was developed for specific detection.
This probe was fabricated based on magnetic SSB (Au MNPs-SSB) microparticles conjugating with detection probe (Apt- SiO2@Au-HRP).
The composite probe has well signal amplification and only requires one-step replacement reaction for color development.
The assay based on the composite probe for CAP detection limit can reach to 0.02 ng/mL.