Effect of the linkers between the zinc fingers in zinc finger protein 809 on gene silencing and nuclear localization
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- 作者：Yu Ichida ; ichida-y@ncchd.go.jp" class="auth_mail" title="E-mail the corresponding author ; Yuko Utsunomiya ; Masafumi Onodera
- 关键词：Retroviral vector ; Kruppel-associated box-containing zinc finger proteins (KRAB-ZFPs) ; Zinc finger protein 809 (ZFP809)
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：18 March 2016
- 年：2016
- 卷：471
- 期：4
- 页码：533-538
- 全文大小：1650 K
文摘
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ZFP809 has three consensus linkers between the zinc fingers.
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Linkers are required for ZFP809 to silence transgene expression driven by MLV-LTR.
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Linkers affect the precise nuclear localization of ZFP809.