Maternal Type 1 diabetes activates stress response in early placenta

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• 作者：Martin Gauster^a ; Alejandro Majali-Martinez^b ; Sabine Maninger^a ; Elisabeth Gutschi^b ; Patrick H. Greimel^b ; Marina Ivanisevic^c ; Josip Djelmis^c ; Gernot Desoye^b ; Ursula Hiden^b ; ^{ursula.hiden@medunigraz.at}
• 关键词：Type 1 diabetes ; Stress response ; Oxidative stress ; First trimester placenta ; Trophoblast
• 刊名：Placenta
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：50
• 期：Complete
• 页码：110-116
• 全文大小：896 K
• 卷排序：50

文摘

Maternal T1DM upregulates stress responsive proteins in early placenta. We conclude that maternal T1DM increases cellular stress in early placenta. Cellular stress may contribute to the risk for pregnancy pathologies associated with T1DM.