Guest Editorial

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• 作者：Sarah E. Pinder ; Elena Provenzano
• 关键词：Chemoradiotherapy ; Neoadjuvant therapy ; Post-treatment pathological change
• 刊名：Current Diagnostic Pathology
• 出版年：2007
• 出版时间：April 2007
• 年：2007
• 卷：13
• 期：2
• 页码：95
• 全文大小：80 K

文摘

Neoadjuvant therapy is increasingly used in the treatment of gastrointestinal malignancies. New molecular target-specific agents also have a role in downstaging hepatic colorectal metastases and metastatic gastrointestinal stromal tumours. Pathologists need to be familiar with post-treatment changes and with tumour regression grading systems. Accurate assessment of specimens is crucial for prognostic purposes and to evaluate therapeutic response. A standardized pathological approach is recommended.