Immune responses to modified live virus vaccines developed from classical or highly pathogenic PRRSV following challenge with a highly pathogenic PRRSV strain
详细信息 查看全文
- 作者：Gang Wanga ; 1 ; Ying Yua ; b ; 1 ; Chong Zhanga ; c ; 1 ; Yabin Tua ; Jie Tonga ; Yonggang Liua ; Yafei Changa ; Chenggang Jianga ; Shujie Wanga ; En-Min Zhoub ; zhouem@nwsuaf.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xuehui Caia ; cai139@hvri.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Highly pathogenic PRRSV ; PRRSV vaccine ; Immune responses
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：62
- 期：Complete
- 页码：1-7
- 全文大小：3135 K
文摘
- •
PRRSV is a costly swine virus that can be controlled through vaccination.
- •
Modified live virus (MLV) vaccines are leading candidates for novel PRRSV vaccines.
- •
The CH-1R vaccine (classical PRRSV) provided some protection against HuN4 infection.
- •
The HuN4-F112 vaccine (highly pathogenic PRRSV) protected against HuN4 infection.
- •
Both vaccines elicited humoral and cellular immune responses.