Time-dependent co-relation of BDNF and CREB mRNAs in adult rat brains following acute psychological stress in the communication box paradigm
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- 作者：Gongying Lia ; 1 ; Yanmei Wangb ; 1 ; Min Yanc ; 1 ; Hongxia Maa ; Yanjie Gaod ; Zexuan Lie ; Changqi Lie ; Hongjun Tianf ; 2 ; hongjuntian_tjmh@163.com" class="auth_mail" title="E-mail the corresponding author ; Chuanjun Zhuod ; f ; 2
- 关键词：Brain-derived neurotrophic factor (BDNF) ; cAMP response element binding protein (CREB) ; Psychological stress ; Physical stress ; Communication box ; In situ hybridization
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：624
- 期：Complete
- 页码：34-41
- 全文大小：1350 K
文摘
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No study has investigated BDNF or CREB modulation in rat brains after acute psychological stress.
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We hypothesize that BDNF and CREB may both be implicated in response to stress in an associated way.
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The BDNF and CREB pathways are involved in the psychological stress response.
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The BDNF and CREB pathways may protect the organism from stress-induced aversive processes.