Perturbation of the Warburg effect increases the sensitivity of cancer cells to TRAIL-induced cell death
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- 作者：Minami Kumazaki ; t3501001@edu.gifu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Haruka Shinohara ; Kohei Taniguchi ; Tomoaki Takai ; Yuki Kuranaga ; Nobuhiko Sugito ; Yukihiro Akao
- 关键词：TRAIL-induced apoptosis ; Warburg effect ; SiR-PTBP1 ; CCN1
- 刊名：Experimental Cell Research
- 出版年：2016
- 出版时间：10 September 2016
- 年：2016
- 卷：347
- 期：1
- 页码：133-142
- 全文大小：2324 K
文摘
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Warburg effect was closely associated with the TRAIL-induced apoptosis.
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Silencing of Warburg effect-related PTBP1 increased sensitivity to the apoptosis.
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PTBP1 could be used as a possible target molecule to conquer the resistance to TRAIL.