Innate immunity, hemostasis and matrix remodeling: PTX3 as a link

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• 作者：Andrea Doni^a ; ^{andrea.doni@humanitasresearch.it} ; Cecilia Garlanda^a ; ^b ; Alberto Mantovani^a ; ^b
• 关键词：Innate immunity ; Inflammation ; Hemostasis ; Extracellular matrix ; Pattern recognition molecule ; Pentraxin 3 (PTX3)
• 刊名：Seminars in Immunology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：28
• 期：6
• 页码：570-577
• 全文大小：1586 K
• 卷排序：28

文摘

Innate immunity and inflammation are functionally connected to hemostasis and extracellular matrix. PTX3 is an essential soluble pattern recognition molecule of innate immune system. PTX3 plays hemostasis-related role in tissue repair. Recognition of microbes and extracellular matrix components are related functions in innate immunity.