The correlation between cerebral arterial pulsatility and cognitive dysfunction in Alzheimer's disease patients

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• 作者：Jae-Sung Lim^a ; Jee Young Lee^b ; Hyung-Min Kwon^b ; Yong-Seok Lee^b ; ^{mercades@snu.ac.kr}
• 关键词：Transcranial Doppler ; Alzheimer's disease ; Pulsatility index ; Alzheimer's Disease Assessment Scale
• 刊名：Journal of the Neurological Sciences
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：373
• 期：Complete
• 页码：285-288
• 全文大小：254 K
• 卷排序：373

文摘

High intracranial pulsatility of anterior circulation was related to the lower cognitive status. Longitudinal increment of pulsatility reflects cognitive decline in Alzheimer disease (AD). Longitudinal decrement of mean flow velocity reflects decline in praxis. Serial assessment of transcranial Doppler might be a useful surrogate for AD progression.