Six Novel Diarylheptanoids Bearing Chalcone or Flavanone Moiety from the Seeds of Alpinia blepharocalyx

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• 作者：Kumar Prasain ; Jeevan ; Tezuka ; Yasuhiro ; Jian ; Jin Li ; Tanaka ; Ken ; Basnet ; Purusotam ; Dong ; Hiu ; et. al.
• 刊名：Tetrahedron
• 出版年：1997
• 出版时间：June 9, 1997
• 年：1997
• 卷：53
• 期：23
• 页码：7833-7842
• 全文大小：553 K

文摘

Six novel diarylheptanoids bearing chalcone or flavanone moiety (1-6) were isolated from the seeds of Alpinia blepharocalyx K. Schum. Their structures were determined by spectroscopic analysis. Stereo-chemical assignment of diarylheptanoid part of these compounds was done by NMR spectral analysis of their MTPA esters. These compounds inhibited nitric oxide (NO) production in endotoxin-activated murine macrophages, J774.1.