After total hip replacement (THR), anticoagulation is recommended up to 35 days.
Both risks of thrombotic and bleeding events have not been assessed at the same time in population-based studies.
We conducted a cross-over cohort from 2007 to 2013 in France, among middle-aged patients.
The risk of pulmonary embolism remains elevated beyond 35 days after THR.
The risk of upper gastrointestinal bleeding is no more elevated beyond 35 days.