One-pot, four-component synthesis of new 3,4,7,8-tetrahydro-3,3-dimethyl-11-aryl-2H-pyridazino[1,2-a]indazole-1,6,9(11H)-triones and 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-triones using an acidic ionic liquid N,N-diethyl-N-sulfoethanammonium chloride ([Et₃N-SO₃H]Cl) as a highly efficient and recyclable catalyst

详细信息    查看全文

• 作者：Behjat Pouramiri ; Esmat Tavakolinejad Kermani ; ^{etavakoly@yahoo.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Multi-component reactions (MCRs) ; Solvent-free conditions ; Pyridazino[1 ; 2-a]indazole-triones ; Indazolo[2 ; 1-b]phthalazine-trione ; Ionic liquid
• 刊名：Tetrahedron Letters
• 出版年：2016
• 出版时间：2 March 2016
• 年：2016
• 卷：57
• 期：9
• 页码：1006-1010
• 全文大小：1622 K

文摘

A rapid and efficient one-pot, four-component protocol for the synthesis of novel 2H-pyridazino[1,2-a]indazole-1,6,9(11H)-triones (6) and 2H-indazolo[2,1-b]phthalazine-1,6,11-triones (7) has been developed using a stable and reusable Brønsted acidic ionic liquid N,N-diethyl-N-sulfoethanammonium chloride ([Et₃N–SO₃H]Cl). A range of diverse aldehydes were successfully applied and the corresponding products obtained in good to excellent yields without any by-products.