Reactions of 7- and 9-aminoadenines with 2,4-pentanedione. Formation of new ring systems, pyridazino[6,1-f]purine and pyridazino[1,6-e]purine

详细信息    查看全文

• 作者：Kaiya ; Toyo ; Saga ; Tetsuya ; Yamagata ; Yuriko ; Kohda ; Kohfuku
• 刊名：Bioorganic and Medicinal Chemistry Letters
• 出版年：1998
• 出版时间：August 18, 1998
• 年：1998
• 卷：8
• 期：16
• 页码：2197-2202
• 全文大小：253 K

文摘

Reactions of 7-aminoadenines with 2,4-pentanedione yielded pyridazino[6,1-f]purines and 5-pyrazolylpyrimidines. The structure of the latter was identified by X-ray analysis. Reaction of 9-amino-N⁶-methyladenine with 2,4-pentanedione gave pyridazino[1,6-e]purine and Schiff base products.