erg20 gene encoding FPP synthase from T. reesei was cloned and functionally analyzed.
The gene overexpressed in T. reesei elevated FPP synthase activity
Dolichyl branch of mevalonate pathway was stimulated in the transformants.
In the erg20 overexpressing strains squalene synthase was inhibited.
Inhibition of squalene synthase did not affect ergosterol level.