Prolactin potentiates the activity of acid-sensing ion channels in female rat primary sensory neurons
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- 作者：Ting-Ting Liu ; Zu-Wei Qu ; Cuixia Ren ; Xiong Gan ; Chun-Yu Qiu ; qiuchunyu1225@126.com" class="auth_mail" title="E-mail the corresponding author ; Wang-Ping Hu ; wangping_hu@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Prolactin ; Acid-sensing ion channel ; Electrophysiology ; Nociceptive behavior ; Dorsal root ganglion neuron
- 刊名：Neuropharmacology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：103
- 期：Complete
- 页码：174-182
- 全文大小：1025 K
文摘
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We provide evidence that prolactin modulated the activity of ASICs in female primary sensory neurons.
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The activation of prolactin receptors contributed to acid- mediated pain.
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Prolactin modulation of on ASICs may be gender-dependent.