Distinct resting-state brain activity in patients with functional constipation
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- 作者：Qiang Zhua ; 1 ; Weiwei Caia ; 1 ; Jianyong Zhengb ; 1 ; Guanya Lia ; Qianqian Menga ; Qiaoyun Liub ; Jizheng Zhaoc ; Karen M. von Deneena ; Yuanyuan Wanga ; Guangbin Cuid ; gbcui@fmmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Shijun Duand ; Yu Hand ; Huaning Wange ; Jie Tiana ; f ; Yi Zhanga ; yizhang@xidian.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yongzhan Nieb ; yongznie@fmmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Functional constipation ; fMRI ; Granger causality ; Resting-state ; Emotional arousal ; Somatic and sensory
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：6 October 2016
- 年：2016
- 卷：632
- 期：Complete
- 页码：141-146
- 全文大小：942 K
文摘
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The pathophysiology of functional constipation is still not completely understood.
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We examined the interactions of brain regions underlying functional constipation.
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Stronger effective connectivity from the frontal cortex propelling limbic circuit.
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Weaker connectivity from sensory and motor control regions to limbic circuit.